In which condition is immunoglobulin M (IgM) or IgG deposition commonly seen?

Immunoglobulin M (IgM) and IgG deposition is commonly associated with systemic lupus erythematosus (SLE), an autoimmune disorder characterized by the body's immune system attacking its own tissues. In SLE, antibodies are produced against a variety of self-antigens, which leads to the formation of immune complexes. These immune complexes can deposit in various tissues, including the skin, kidneys, and joints, causing inflammation and damage.

The presence of IgM and IgG antibodies is a hallmark of this disease and can contribute to the characteristic features and complications seen in patients. Clinically, these deposits contribute to symptoms such as inflammation of the joints (arthritis), skin rashes, and nephritis, which is often seen in SLE patients.

The other conditions listed do not typically present with the deposition of immunoglobulins in the same way SLE does. For instance, hemolytic anemia may involve specific antibody-mediated destruction of red blood cells but does not generally result in widespread immunoglobulin deposition. Chronic lymphocytic leukemia is a hematologic malignancy that involves proliferation of B-lymphocytes and typically does not feature prominent immune complex deposition. Wolff-Parkinson-White syndrome is a cardiac condition related to electrical