Which serological markers are present during acute Hepatitis B infection?

During acute Hepatitis B infection, the serological markers that are typically present include HBsAg, HBeAg, and Anti-HBc (IgM).

HBsAg, or Hepatitis B surface antigen, is the first serological marker to appear during an acute infection and indicates that the virus is present in the blood. Its presence is crucial for establishing an active Hepatitis B infection.

HBeAg, or Hepatitis B e antigen, signifies a higher level of viral replication and infectivity. The presence of HBeAg indicates that the virus is actively replicating and the patient is highly infectious.

Anti-HBc (IgM) is the immunoglobulin M antibody to the Hepatitis B core antigen, which also appears early during an acute infection. The detection of IgM specifically signifies recent infection, as it is produced shortly after the initial exposure to the virus.

The combination of these markers provides clear evidence of acute Hepatitis B infection and is critical for diagnosis and management of the disease.